?? ???? ????? ???? ????? ?? ?????? ??????? ?????? ?????? ??? ???? ????? ?? ??? ???????? ??? ?? ??? ????? ???? ????? ?? ???? ?? ??? ???? ??????? ?? ?????? ????? ???? ?????? ????? ??????.?????? ????? ?????? ??? ???????? ??????? ?? ??? ???? ??? ?? ???????.Usage of opioids for an extended period of time could cause reduced fertility in females and male